Costa keeps winning run going
The Ecuadorian saw yellow after 31 minutes for a late challenge on Danny Rose, earning him an automatic one-match ban.
The news will be a blow to Jose Mourinho who will be forced into a reshuffle, with Valencia having established himself as first-choice right-back this season.
However, the Portuguese does have options with Matteo Darmian, who has featured at left-back recently, one alternative while Timothy Fosu-Mensah could also come into the team.
United head to Selhurst Park on Wednesday to face a Palace side just three points off the drop zone and with just one win in their last nine games.
