With John Brooks sidelined, the U.S. coach has again turned to the duo that started last month’s 1-1 draw with Honduras after Cameron and Tim Ream made notable miscues in a 2-0 loss to Costa Rica.
Arena also has left Clint Dempsey — currently tied with Landon Donovan as the Americans’ all-time leading scorer with 57 goals — as a substitute, giving the nod to Jozy Altidore and Bobby Wood up front.
Tim Howard gets the start in goal after splitting the September qualifiers with Brad Guzan, while DeAndre Yedlin and Jorge Villafana start at outside back.
Captain Michael Bradley anchors a midfield that also features Darlington Nagbe, Christian Pulisic and Paul Arriola.
USA XI: Howard; Yedlin, Gonzalez, Besler, Villafana; Arriola, Bradley, Nagbe; Pulisic; Wood, Altidore
Substitutes: Guzan, Rimando, Cameron, Ream, Zusi, Beasley, McCarty, Acosta, Bedoya, Feilhaber, Dempsey, Wondolowski
Scratched: Orozco, Agudelo
Panama XI: Penedo; Murillo, Torres, Baloy, Ovalle; Quintero, Gomez, Godoy, Barcenas; Torres, Perez
Substitutes: Calderon, Escobar, Vargas, Machado, Davis, Buitrago, Cooper, Gonzalez, Tejada, Nurse, Arroyo
